From I-35: Take exit 186 (Fir St. / U.S. 64) toward Perry. Proceed appx. 1/4 mile east. Cherokee Strip Museum is located on the left (North) side of the highway.

From Tulsa: Take the Morrison exit (U.S. 64) off of the Cimarron Turnpike. Proceed appx. 15 miles to Perry. Continue west on Fir Ave / U.S. 64 through 3 stop lights toward I-35. You will reach the Cherokee Strip Museum about 1/4 mile before I-35 on the right (North) side of the highway.